A recent study by Laird et al., published in BMC Chemistry, investigates the potential of INNOTERE Plotter-Paste-CPC for manufacturing gene-activating 3D-printed scaffolds. For the first time, this approach describes local gene activation of cells by adsorbing plasmid DNA containing cationic polyplexes onto the scaffold surface, providing an alternative to conventional drug delivery methods like surface modification with BMP-2. The findings suggest that this method could offer a promising new strategy for supporting bone regeneration in large defects.
